MALARIA PAN/PF

Description

Rapid Lateral Flow Malaria Test – Pan/Pf Detection

The Rapid Lateral Flow Malaria Test (Pan/Pf) is an innovative point-of-care diagnostic tool designed for the swift detection of malaria infections, including Plasmodium falciparum (Pf) and non-falciparum species (Pan). This test is essential for timely diagnosis and effective management of malaria, particularly in endemic regions and resource-limited settings.

Key Features:

• Dual Detection Capability: Simultaneously detects Plasmodium falciparum specific antigens and pan-specific malaria antigens, ensuring comprehensive screening for all malaria-causing species.
• Rapid Results: Delivers results within 15–20 minutes, allowing for prompt treatment decisions.
• User-Friendly Design: Simple procedure requiring minimal training, suitable for use in both clinical laboratories and field settings.
• Portability: Lightweight and compact design ideal for remote locations and emergency situations.
• High Sensitivity and Specificity: Rigorously validated to minimize false positives and negatives, ensuring reliable diagnosis.
• Minimal Equipment Required: Does not require complex laboratory infrastructure, making it accessible in low-resource environments.

How It Works:

The test employs lateral flow immunochromatography. A small sample (typically blood) is applied to the sample pad, where it mixes with labeled detection antibodies. As the mixture migrates along the nitrocellulose membrane, malaria-specific antigens bind to immobilized capture antibodies arranged in distinct test lines:

• Pf Line: Specific for Plasmodium falciparum antigens.
• Pan Line: Targets common antigens shared by all malaria species.

A separate control line confirms the proper flow and function of the test, validating the test result.

Applications:

• Clinical Diagnosis: Facilitates rapid malaria diagnosis in healthcare facilities, enabling early initiation of appropriate antimalarial therapy.
• Field and Community Screening: Ideal for outreach programs and mass screening campaigns in endemic areas.
• Emergency Settings: Its rapid turnaround time supports urgent decision-making in high-risk situations.